American scientists and engineers will power the super intelligence (SI) revolution in science and innovation through the Genesis Mission. DOE SC hereby invites applications from United States (U.S.) Institutions of Higher Education and domestic doctoral-granting institutions to develop and demonstrate the effectiveness of novel four-year doctoral training pilots with dual competency in SI and another scientific discipline. Two high-impact research experiences are required as part of the pilot, one at a DOE National Laboratory or SC user facility and one in industry. The purpose of this pilot is to lay the foundation for the first cohort of Genesis Mission Graduate Fellows, representing a new generation of Ph.D.-level scientists and engineers with exceptional training in SI and scientific disciplines along with practical research experiences. All graduate fellowships supported by this NOFO must support research activities related to SC-relevant Genesis Mission National Science and Technology Challenges as detailed in the Request for Applications (RFA), DE-FOA-0003612.
Genesis Mission Graduate Fellowship Pilot
Office of Science · Opportunity number DE-FOA-0003673
Details summarized from the official notice as of Oct 16, 2026. Always confirm eligibility, deadlines and requirements in the official notice before applying.
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Key facts
| Opportunity number | DE-FOA-0003673 |
|---|---|
| Agency | Office of Science Department of Energy - Office of Science |
| Assistance listing (ALN, formerly CFDA) | 81.049 |
| Posted | Oct 8, 2026 |
| Deadline | Jan 12, 2027 |
| Award ceiling | $20,000,000 |
| Award floor | $20,000,000 |
| Expected number of awards | 5 |
| Estimated total program funding | $100,000,000 |
| Cost sharing or matching required | No |
| Funding type | Grant |
| Category | Science technology and other research and development |
| Last updated here | Oct 16, 2026 |
Summary from the notice
Who can apply
The official notice lists these applicant types as eligible:
- Private colleges and universities
- Others named in the notice (see the eligibility text)
- Public and state colleges and universities
Who should take a closer look
- Colleges and universities
Not listed as eligible
- Small businesses
- Nonprofits
- State governments
- Local governments
- Tribal governments and organizations
- Larger for-profit companies
- Individuals
Unless the eligibility text in the notice names you, this opportunity is probably not for you.
Eligibility details from the notice
In accordance with 2 C.F.R. § 910.126, Competition, eligibility for award is restricted to U.S. Institutions of Higher Education and domestic doctoral-granting institutions as the lead applicant. This restriction on the lead applicant is necessary because only institutions of higher education and doctoral-granting institutions offer doctoral training programs. Applications may include subawards to institutions of higher education, industry, DOE National Laboratories, and SC user facilities.
Registrations you will likely need
Most applications submitted through Grants.gov need the following. Registration can take several weeks, so start early. The notice lists the exact requirements.
- SAM.gov registration for your organization, which also gives you a Unique Entity ID (UEI). Registration is free.
- A Login.gov account, which Grants.gov uses for sign-in.
- A Grants.gov applicant registration linked to your organization's UEI.
Past awards for this program
Totals for assistance listing 81.049 from public USASpending.gov data, as of Oct 4, 2026. Past awards do not predict future funding.
| Year | Listing | Awards | Total | Average |
|---|---|---|---|---|
| 2026 | 81.049 | 8 | $2,614,705,481 | $326,838,185 |
| 2025 | 81.049 | 6 | $2,459,858,607 | $409,976,435 |
| 2024 | 81.049 | 7 | $3,295,941,042 | $470,848,720 |
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