Open federal grants for for-profit businesses
395 open opportunities as of Oct 16, 2026.
Independent platform. Not affiliated with or endorsed by any government agency. Data from public federal sources.
Some federal notices are open to for-profit organizations of any size. These are listed separately from small businesses on Grants.gov. A program that lists only "small businesses" is not open to larger companies.
The list below shows every open opportunity in our database whose official notice lists for-profit businesses as an eligible applicant type. Each listing links to a summary page and to the official notice.
Being in an eligible group is only the first check. Read the eligibility section of each notice for location, program focus, cost sharing and other conditions before you start an application.
Open opportunities
Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Not Allowed)
National Institutes of Health · PA-24-191
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Required)
National Institutes of Health · PA-24-193
New Approaches for Measuring Brain Changes Across Longer Timespans (R21 Clinical Trial Optional)
National Institutes of Health · PAR-25-272
Summer Research Education Experience Program (R25 Clinical Trial Not Allowed)
National Institutes of Health · PAR-24-204
New Approaches for Measuring Brain Changes Across Longer Timespans (R01 Clinical Trial Optional)
National Institutes of Health · PAR-25-279
Pilot Health Services and Economic Research on the Treatment of Drug, Alcohol, and Tobacco Use Disorders (R34 Clinical Trial Optional)
National Institutes of Health · PAR-25-100
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)
National Institutes of Health · PA-24-176
Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Required)
National Institutes of Health · PA-24-190
NIDCD Research Career Enhancement Award for Established Investigators (K18 Clinical Trial Not Allowed)
National Institutes of Health · PAR-24-143
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)
National Institutes of Health · PA-24-185
NIDCD Research Career Enhancement Award for Established Investigators (K18 Clinical Trial Required)
National Institutes of Health · PAR-24-140
Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Required)
National Institutes of Health · PA-24-187
Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Not Allowed)
National Institutes of Health · PA-24-188
NIDCD Mentored Career Development Award for Postdoctorate Au.D./Ph.D. Audiologists (K01 Clinical Trial Required)
National Institutes of Health · PAR-24-149
Independent Scientist Award (Parent K02 - Independent Clinical Trial Required)
National Institutes of Health · PA-24-178
NIDCD Mentored Career Development Award for Postdoctorate Au.D./Ph.D. Audiologists (K01 Independent Clinical Trial Not Allowed)
National Institutes of Health · PAR-24-159
Independent Scientist Award (Parent K02 - Independent Clinical Trial Not Allowed)
National Institutes of Health · PA-24-179
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)
National Institutes of Health · PA-24-194
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)
National Institutes of Health · PA-24-182
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Required)
National Institutes of Health · PA-24-181
Frequently asked questions
Does being listed as eligible mean my organization qualifies?
No. The applicant type is only the first filter. Most notices add more conditions, such as location, program focus, matching funds or prior experience. Read the eligibility section of the official notice before you apply.
Is GovGrantsUSA a government website?
No. GovGrantsUSA is an independent platform operated by VRLY Ventures LLC. It is not affiliated with or endorsed by any government agency. Opportunity details are summarized from public federal sources such as Grants.gov.
Does it cost anything to apply for a federal grant?
Searching for and applying to federal grants on Grants.gov is free. Be wary of anyone who asks for a fee to "release" a grant or guarantees an award.
How current is this information?
Listings are refreshed from public federal data every day, and each page shows when it was last updated. Agencies can change or cancel a notice at any time, so always confirm details in the official notice.
What do I need before I can apply?
Most applicants through Grants.gov need an active SAM.gov registration with a Unique Entity ID (UEI), a Login.gov account and a Grants.gov account linked to their organization. Registration can take several weeks, so start early.