Open federal grants for tribal governments and organizations
450 open opportunities as of Oct 16, 2026.
Independent platform. Not affiliated with or endorsed by any government agency. Data from public federal sources.
Many federal programs list federally recognized tribal governments and other Native American tribal organizations as eligible, and some are set aside for tribal applicants. Notices often have specific documentation requirements, such as a tribal resolution.
The list below shows every open opportunity in our database whose official notice lists tribal governments and organizations as an eligible applicant type. Each listing links to a summary page and to the official notice.
Being in an eligible group is only the first check. Read the eligibility section of each notice for location, program focus, cost sharing and other conditions before you start an application.
Open opportunities
Full-Scale Hybrid Effectiveness-Implementation Trials for Mental Health Interventions (R01 - Clinical Trial Required)
National Institutes of Health · PAR-25-177
Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R33 Clinical Trial Required)
National Institutes of Health · PAR-25-181
Pilot Hybrid Effectiveness-Implementation Trials for Mental Health Interventions (R01 Clinical Trial Required)
National Institutes of Health · PAR-25-178
Confirmatory Efficacy Clinical Trials of Non-Pharmacological and Pharmacological Interventions for Mental Disorders (R01 Clinical Trial Required)
National Institutes of Health · PAR-25-179
Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R61/R33 Clinical Trial Required)
National Institutes of Health · PAR-25-182
First in Human and Early Stage Clinical Trials of Novel Investigational Drugs or Neuromodulatory Device-based Interventions for Psychiatric Disorders (U01 Clinical Trial Required)
National Institutes of Health · PAR-25-180
Early Stage Testing of Pharmacologic or Neuromodulatory Device-based Interventions for the Treatment of Mental Disorders (R61/R33 Clinical Trial Required)
National Institutes of Health · PAR-25-184
NIDCD Early Career Research(ECR) Award (R21 Clinical Trial Optional)
National Institutes of Health · PAR-25-120
NEI Research Grant for Vision-Related Secondary Data Analysis (R21 Clinical Trial Not Allowed)
National Institutes of Health · PAR-25-357
NIDCD Cooperative Agreement for Clinical Trials in Communication Disorders (U01 - Clinical Trial Required)
National Institutes of Health · PAR-25-343
Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional)
National Institutes of Health · RFA-CA-27-019
Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Neurotherapeutic Agent Characterization and In vivo Efficacy Studies (R61/R33 Clinical Trial Not Allowed)
National Institutes of Health · PAR-25-225
Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Assay Development and Neurotherapeutic Agent Identification (R61/R33 Clinical Trial Not Allowed)
National Institutes of Health · PAR-25-059
Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Development and Validation of Model Systems to Facilitate Neurotherapeutic Discovery (R61/R33 Clinical Trial Not Allowed)
National Institutes of Health · PAR-25-060
Cancer Prevention and Control Clinical Trials Planning Grant Program (U34 Clinical Trials Optional)
National Institutes of Health · PAR-25-103
Cancer Prevention and Control Clinical Trials Planning Grant Program (R34 Clinical Trials Optional)
National Institutes of Health · PAR-25-104
National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders (U19 Clinical Trial Optional)
National Institutes of Health · PAR-25-353
National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders (U01 Clinical Trial Optional)
National Institutes of Health · PAR-25-352
Mechanistic Evaluation of Therapeutic Targets derived from Treatable Traits to Improve CNS Outcomes in People with HIV (R21/R33 Clinical Trial Not Allowed)
National Institutes of Health · RFA-MH-27-125
Alzheimer's Drug-Development Program (U01 Clinical Trial Optional)
National Institutes of Health · PAR-25-297
Frequently asked questions
Does being listed as eligible mean my organization qualifies?
No. The applicant type is only the first filter. Most notices add more conditions, such as location, program focus, matching funds or prior experience. Read the eligibility section of the official notice before you apply.
Is GovGrantsUSA a government website?
No. GovGrantsUSA is an independent platform operated by VRLY Ventures LLC. It is not affiliated with or endorsed by any government agency. Opportunity details are summarized from public federal sources such as Grants.gov.
Does it cost anything to apply for a federal grant?
Searching for and applying to federal grants on Grants.gov is free. Be wary of anyone who asks for a fee to "release" a grant or guarantees an award.
How current is this information?
Listings are refreshed from public federal data every day, and each page shows when it was last updated. Agencies can change or cancel a notice at any time, so always confirm details in the official notice.
What do I need before I can apply?
Most applicants through Grants.gov need an active SAM.gov registration with a Unique Entity ID (UEI), a Login.gov account and a Grants.gov account linked to their organization. Registration can take several weeks, so start early.