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Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)

National Institutes of Health · Opportunity number PAR-27-022

View the official notice on Grants.gov
624 days left (deadline Jul 1, 2028)

Details summarized from the official notice as of Oct 16, 2026. Always confirm eligibility, deadlines and requirements in the official notice before applying.

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Key facts

Opportunity numberPAR-27-022
AgencyNational Institutes of Health
Department of Health and Human Services
Assistance listing (ALN, formerly CFDA)93.351, 93.855, 93.866, 93.867, 93.310, 93.859
PostedJun 25, 2026
DeadlineJul 1, 2028
Award ceiling$5,000,000
Award floor$300,000
Cost sharing or matching requiredNo
Funding typeGrant
CategoryHealth
Last updated hereOct 16, 2026

Summary from the notice

This Notice of Funding Opportunity (NOFO) announces the restructured Shared Instrumentation Grant (SIG) Program that consolidates three existing shared-use instrumentation programs, i.e., the Shared Instrumentation Grant program, the High-End Instrumentation Grant program, and the Basic Instrumentation Grant program. The NOFO invites applications from groups of NIH-supported investigators to purchase or upgrade a single state-of-the-art commercially available instrument or an integrated instrumentation system. The instruments purchased through the SIG Program are required to be optimally shared among the users to ensure efficient and cost-effective research operations, enable rigorous and reproducible measurements, and encourage collaborative research and benefit broad research communities at large. The minimum award is $300,000. There is no cap on the total cost of the instrument; however, the maximum award is $5,000,000. Cost sharing is required for premium instruments or special use instruments.

Who can apply

The official notice lists these applicant types as eligible:

  • Private colleges and universities
  • Special district governments
  • Nonprofits with 501(c)(3) status (other than colleges)
  • Nonprofits without 501(c)(3) status (other than colleges)
  • County governments
  • Independent school districts
  • Other Native American tribal organizations
  • State governments
  • City or township governments
  • Others named in the notice (see the eligibility text)
  • Public and Indian housing authorities
  • For-profit organizations other than small businesses
  • Federally recognized tribal governments
  • Small businesses
  • Public and state colleges and universities

Who should take a closer look

  • Small businesses
  • Nonprofits
  • Colleges and universities
  • State governments
  • Local governments
  • Tribal governments and organizations
  • Larger for-profit companies

Not listed as eligible

  • Individuals

Unless the eligibility text in the notice names you, this opportunity is probably not for you.

Eligibility details from the notice

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Registrations you will likely need

Most applications submitted through Grants.gov need the following. Registration can take several weeks, so start early. The notice lists the exact requirements.

Past awards for this program

Totals for assistance listing 93.351, 93.855, 93.866, 93.867, 93.310, 93.859 from public USASpending.gov data, as of Mar 26, 2026. Past awards do not predict future funding.

YearListingAwardsTotalAverage
2026 93.855 1 $1,062,954,652 $1,062,954,652

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