The purpose of this notice of funding opportunity (NOFO) is to support implementation research on strategies to improve the uptake, implementation, sustainment, scale and/or spread of evidence-based prevention, treatment, and care interventions in communities in the U.S. significantly impacted by HIV. Projects should be large in scale with high potential for research and public health impact. Specifically, large single site studies, multi-site studies, and comparative studies are encouraged as scientifically appropriate.
Open for applications
Implementation Science to Advance HIV Prevention, Treatment, and Care (R61/R33 Clinical Trial Optional)
National Institutes of Health · Opportunity number RFA-AI-27-018
View the official notice on Grants.gov
978 days left
(deadline Jun 20, 2029)
Details summarized from the official notice as of Oct 16, 2026. Always confirm eligibility, deadlines and requirements in the official notice before applying.
Independent platform. Not affiliated with or endorsed by any government agency. Data from public federal sources.
Key facts
| Opportunity number | RFA-AI-27-018 |
|---|---|
| Agency | National Institutes of Health Department of Health and Human Services |
| Assistance listing (ALN, formerly CFDA) | 93.847, 93.279, 93.837, 93.839, 93.866, 93.313, 93.838, 93.879, 93.310, 93.393, 93.846, 93.361, 93.121, 93.242, 93.394, 93.840, 93.855, 93.307, 93.865, 93.233, 93.273, 93.399 |
| Posted | Oct 6, 2026 |
| Deadline | Jun 20, 2029 |
| Expected number of awards | 10 |
| Estimated total program funding | $7,000,000 |
| Cost sharing or matching required | No |
| Funding type | Grant |
| Category | Health |
| Last updated here | Oct 16, 2026 |
Summary from the notice
Who can apply
The official notice lists these applicant types as eligible:
- City or township governments
- Others named in the notice (see the eligibility text)
- Public and state colleges and universities
- For-profit organizations other than small businesses
- Small businesses
- State governments
- County governments
- Public and Indian housing authorities
- Private colleges and universities
- Special district governments
- Federally recognized tribal governments
- Other Native American tribal organizations
- Nonprofits without 501(c)(3) status (other than colleges)
- Independent school districts
- Nonprofits with 501(c)(3) status (other than colleges)
Who should take a closer look
- Small businesses
- Nonprofits
- Colleges and universities
- State governments
- Local governments
- Tribal governments and organizations
- Larger for-profit companies
Not listed as eligible
- Individuals
Unless the eligibility text in the notice names you, this opportunity is probably not for you.
Eligibility details from the notice
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
Registrations you will likely need
Most applications submitted through Grants.gov need the following. Registration can take several weeks, so start early. The notice lists the exact requirements.
- SAM.gov registration for your organization, which also gives you a Unique Entity ID (UEI). Registration is free.
- A Login.gov account, which Grants.gov uses for sign-in.
- A Grants.gov applicant registration linked to your organization's UEI.
Past awards for this program
Totals for assistance listing 93.847, 93.279, 93.837, 93.839, 93.866, 93.313, 93.838, 93.879, 93.310, 93.393, 93.846, 93.361, 93.121, 93.242, 93.394, 93.840, 93.855, 93.307, 93.865, 93.233, 93.273, 93.399 from public USASpending.gov data, as of Mar 26, 2026. Past awards do not predict future funding.
| Year | Listing | Awards | Total | Average |
|---|---|---|---|---|
| 2026 | 93.855 | 1 | $1,062,954,652 | $1,062,954,652 |
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