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Limited Competition: Superfund Hazardous Substance Research and Training Program (P42 Clinical Trial Optional)

National Institutes of Health · Opportunity number RFA-ES-27-004

View the official notice on Grants.gov
710 days left (deadline Sep 25, 2028)

Details summarized from the official notice as of Oct 16, 2026. Always confirm eligibility, deadlines and requirements in the official notice before applying.

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Key facts

Opportunity numberRFA-ES-27-004
AgencyNational Institutes of Health
Department of Health and Human Services
Assistance listing (ALN, formerly CFDA)93.143
PostedMay 19, 2026
DeadlineSep 25, 2028
Award ceiling$1,750,000
Expected number of awards10
Estimated total program funding$22,000,000
Cost sharing or matching requiredNo
Funding typeGrant
CategoryHealth
Last updated hereOct 16, 2026

Summary from the notice

The National Institute of Environmental Health Sciences (NIEHS) is announcing the continuation of the Superfund Hazardous Substance Research and Training Program, referred to as Superfund Research Program (SRP) Centers. SRP Center grants will support problem-based, solution-oriented research Centers that consist of multiple, integrated projects representing both the biomedical and environmental science and engineering disciplines; as well as cores tasked with administrative (which includes Center leadership, data management, and training); translational research and engagement; and research support functions. The scope of the SRP Centers is taken directly from the Superfund Amendments and Reauthorization Act of 1986, which limits competition for this program to accredited institutes of higher education.Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.

Who can apply

The official notice lists these applicant types as eligible:

  • Private colleges and universities
  • Public and state colleges and universities

Who should take a closer look

  • Colleges and universities

Not listed as eligible

  • Small businesses
  • Nonprofits
  • State governments
  • Local governments
  • Tribal governments and organizations
  • Larger for-profit companies
  • Individuals

Unless the eligibility text in the notice names you, this opportunity is probably not for you.

Eligibility details from the notice

Based on 42 USC 9660(a)(3) eligible applicants are limited to accredited institutes of higher education. Eligible applicants are permitted under the law, and encouraged by NIEHS, to subcontract as appropriate with other organizations as necessary to conduct portions of the research. Examples of other organizations may include generators of hazardous wastes; persons involved in the detection, assessment, evaluation, and treatment of hazardous substances; owners and operators of facilities at which hazardous substances are located; and/or State and local governments. Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Registrations you will likely need

Most applications submitted through Grants.gov need the following. Registration can take several weeks, so start early. The notice lists the exact requirements.

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