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GREGoRi Technology Integration Center (U01, Clinical Trials Optional)

National Institutes of Health · Opportunity number RFA-HG-27-012

View the official notice on Grants.gov
14 days left (deadline Oct 30, 2026)

Details summarized from the official notice as of Oct 16, 2026. Always confirm eligibility, deadlines and requirements in the official notice before applying.

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Key facts

Opportunity numberRFA-HG-27-012
AgencyNational Institutes of Health
Department of Health and Human Services
Assistance listing (ALN, formerly CFDA)93.172
PostedJun 18, 2026
DeadlineOct 30, 2026
Award ceiling$2,250,000
Expected number of awards1
Estimated total program funding$3,000,000
Cost sharing or matching requiredNo
Funding typeCooperative agreement
CategoryHealth
Last updated hereOct 16, 2026

Summary from the notice

The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. The purpose of this Notice of Funding Opportunity is to establish the GREGoRi Technology Integration Center, which will enable the development of standards and best practices for applying new and emerging molecular methods in rare disease diagnosis. A major deliverable of the Center will be a multidimensional dataset that can be used for the development and benchmarking of novel tools and strategies that facilitate rare disease diagnosis.

Who can apply

The official notice lists these applicant types as eligible:

  • County governments
  • Public and Indian housing authorities
  • Other Native American tribal organizations
  • For-profit organizations other than small businesses
  • City or township governments
  • Special district governments
  • Independent school districts
  • Nonprofits with 501(c)(3) status (other than colleges)
  • Small businesses
  • Federally recognized tribal governments
  • Nonprofits without 501(c)(3) status (other than colleges)
  • Others named in the notice (see the eligibility text)
  • Public and state colleges and universities
  • State governments
  • Private colleges and universities

Who should take a closer look

  • Small businesses
  • Nonprofits
  • Colleges and universities
  • State governments
  • Local governments
  • Tribal governments and organizations
  • Larger for-profit companies

Not listed as eligible

  • Individuals

Unless the eligibility text in the notice names you, this opportunity is probably not for you.

Eligibility details from the notice

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Registrations you will likely need

Most applications submitted through Grants.gov need the following. Registration can take several weeks, so start early. The notice lists the exact requirements.

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