INCLUDE Project: Transformative Research Awards for Down syndrome (R01 Clinical Trial Not Allowed)
National Institutes of Health · Opportunity number RFA-OD-27-004
Details summarized from the official notice as of Oct 16, 2026. Always confirm eligibility, deadlines and requirements in the official notice before applying.
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Key facts
| Opportunity number | RFA-OD-27-004 |
|---|---|
| Agency | National Institutes of Health Department of Health and Human Services |
| Assistance listing (ALN, formerly CFDA) | 93.867, 93.310, 93.846, 93.855, 93.395, 93.847, 93.351, 93.838, 93.866, 93.837, 93.121, 93.233, 93.839, 93.865, 93.879, 93.350, 93.173, 93.242, 93.840 |
| Posted | May 12, 2026 |
| Deadline | Jun 15, 2028 |
| Award ceiling | $500,000 |
| Expected number of awards | 4 |
| Estimated total program funding | $3,000,000 |
| Cost sharing or matching required | No |
| Funding type | Grant |
| Category | Health |
| Last updated here | Oct 16, 2026 |
Summary from the notice
Who can apply
The official notice lists these applicant types as eligible:
- County governments
- Federally recognized tribal governments
- City or township governments
- Public and Indian housing authorities
- Public and state colleges and universities
- Private colleges and universities
- Nonprofits with 501(c)(3) status (other than colleges)
- Nonprofits without 501(c)(3) status (other than colleges)
- Independent school districts
- Others named in the notice (see the eligibility text)
- For-profit organizations other than small businesses
- Other Native American tribal organizations
- Small businesses
- State governments
- Special district governments
Who should take a closer look
- Small businesses
- Nonprofits
- Colleges and universities
- State governments
- Local governments
- Tribal governments and organizations
- Larger for-profit companies
Not listed as eligible
- Individuals
Unless the eligibility text in the notice names you, this opportunity is probably not for you.
Eligibility details from the notice
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Registrations you will likely need
Most applications submitted through Grants.gov need the following. Registration can take several weeks, so start early. The notice lists the exact requirements.
- SAM.gov registration for your organization, which also gives you a Unique Entity ID (UEI). Registration is free.
- A Login.gov account, which Grants.gov uses for sign-in.
- A Grants.gov applicant registration linked to your organization's UEI.
Past awards for this program
Totals for assistance listing 93.867, 93.310, 93.846, 93.855, 93.395, 93.847, 93.351, 93.838, 93.866, 93.837, 93.121, 93.233, 93.839, 93.865, 93.879, 93.350, 93.173, 93.242, 93.840 from public USASpending.gov data, as of Mar 26, 2026. Past awards do not predict future funding.
| Year | Listing | Awards | Total | Average |
|---|---|---|---|---|
| 2026 | 93.855 | 1 | $1,062,954,652 | $1,062,954,652 |
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