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Open federal grants for nonprofits

472 open opportunities as of Oct 16, 2026.

Independent platform. Not affiliated with or endorsed by any government agency. Data from public federal sources.

Many federal programs list nonprofits as eligible, and notices often split them into two groups: nonprofits with 501(c)(3) status from the IRS and nonprofits without it. Check which group the notice names. Colleges and universities are usually listed separately even when they are nonprofits.

The list below shows every open opportunity in our database whose official notice lists nonprofits as an eligible applicant type. Each listing links to a summary page and to the official notice.

Being in an eligible group is only the first check. Read the eligibility section of each notice for location, program focus, cost sharing and other conditions before you start an application.

Open opportunities

NIH Research Program Projects (Parent P01 Clinical Trial Optional)

National Institutes of Health · PA-27-061

Deadline: May 25, 2029 (952 days left) Health

Limited Competition: Centers of Biomedical Research Excellence: Development Phase (COBRE-D) (P30 - Clinical Trial Not Allowed)

National Institutes of Health · PAR-27-054

Deadline: May 26, 2029 (953 days left) Health

Limited Competition: Institutional Development Award (IDeA) for Clinical & Translational Research (CTR) (P30 - CT Optional)

National Institutes of Health · PAR-27-056

Deadline: May 30, 2029 (957 days left) Health

Implementation Science to Advance HIV Prevention, Treatment, and Care (R61/R33 Clinical Trial Optional)

National Institutes of Health · RFA-AI-27-018

Deadline: Jun 20, 2029 (978 days left) Health

Research Opportunities in Cancer Epidemiology Cohort Studies (U01 Clinical Trial Not Allowed)

National Institutes of Health · PAR-27-073

Deadline: Jul 5, 2029 (993 days left) Health

Bioengineering Research Grants (BRG) (R01 Clinical Trial Optional)

National Institutes of Health · PAR-27-072

Deadline: Jul 5, 2029 (993 days left) Up to: $500,000 Health

Causal Hypotheses on the Oral-Systemic Health Impacts of Human Behaviors among People with Chronic Conditions (U01 Clinical Trial Not Allowed)

National Institutes of Health · PAR-27-057

Deadline: Jul 5, 2029 (993 days left) Up to: $500,000 Health

NIAID Clinical Trial Implementation Cooperative Agreement (U01 Clinical Trial Required)

National Institutes of Health · PAR-27-064

Deadline: Jul 5, 2029 (993 days left) Health

NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Clinical Trial Not Allowed)

National Institutes of Health · PAR-27-058

Deadline: Jul 5, 2029 (993 days left) Up to: $500,000 Health

Academic Career Excellence (ACE) Award (K32 Independent Clinical Trial Not Allowed)

National Institutes of Health · PAR-27-062

Deadline: Jul 12, 2029 (1000 days left) Health

Institutional Mentored Career Development Award (Parent K12) (Clinical Trials Not Allowed)

National Institutes of Health · PA-27-030

Deadline: Jul 12, 2029 (1000 days left) Health

Limited Competition: Small Grant Program for Mentored Research Career Development Award Recipients (R03) (Clinical Trials Not Allowed)

National Institutes of Health · PAR-27-074

Deadline: Jul 16, 2029 (1004 days left) Health

Air Force Basic Research Sciences Conference and Workshop Support

Air Force Office of Scientific Research · FA955026S0002

Deadline: Aug 31, 2029 (1050 days left) Up to: $2,000,000 Science technology and other research and development

Specialized Programs of Research Excellence (SPOREs) in Human Cancers for Years 2027, 2028, and 2029 (P50 Clinical Trial Required)

National Institutes of Health · PAR-28-022

Deadline: Sep 25, 2029 (1075 days left) Health

Collaborative Program Grant for Interdisciplinary Teams (RM1 Clinical Trial Optional)

National Institutes of Health · PAR-27-003

Deadline: Sep 26, 2029 (1076 days left) Health

Early-Onset Cancers: Investigating Etiology, Mechanisms, and Early Detection Strategies (RP1 Clinical Trials Optional)

National Institutes of Health · PAR-28-014

Deadline: Oct 11, 2029 (1091 days left) Health

Pancreatic Cancer Detection Consortium: Research Units (U01 Clinical Trial Optional)

National Institutes of Health · PAR-28-056

Deadline: Nov 5, 2029 (1116 days left) Up to: $600,000 Health

Palliative Care Research Across the Lifespan: Leveraging the Palliative Care Consortium (R01 Clinical Trial Optional)

National Institutes of Health · PAR-27-090

Deadline: Nov 5, 2029 (1116 days left) Health

NEI Translational Research Program for Therapeutics (R61/R33 Clinical Trial Not Allowed)

National Institutes of Health · PAR-28-072

Deadline: Nov 16, 2029 (1127 days left) Health

Frequently asked questions

Does being listed as eligible mean my organization qualifies?

No. The applicant type is only the first filter. Most notices add more conditions, such as location, program focus, matching funds or prior experience. Read the eligibility section of the official notice before you apply.

Is GovGrantsUSA a government website?

No. GovGrantsUSA is an independent platform operated by VRLY Ventures LLC. It is not affiliated with or endorsed by any government agency. Opportunity details are summarized from public federal sources such as Grants.gov.

Does it cost anything to apply for a federal grant?

Searching for and applying to federal grants on Grants.gov is free. Be wary of anyone who asks for a fee to "release" a grant or guarantees an award.

How current is this information?

Listings are refreshed from public federal data every day, and each page shows when it was last updated. Agencies can change or cancel a notice at any time, so always confirm details in the official notice.

What do I need before I can apply?

Most applicants through Grants.gov need an active SAM.gov registration with a Unique Entity ID (UEI), a Login.gov account and a Grants.gov account linked to their organization. Registration can take several weeks, so start early.